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Medical

NAPLEX

North American Pharmacist Licensure Examination

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Question: 31

Which of the following is an anxiolytic?

1. Buspirone

2. Budenoside

3. Busulfan

4. Bumetanide

Answer: A

Buspirone is an anxiolytic. Budenoside is a corticosteroid used as an inhalant for asthma therapy. Busulfan is an alkylating agents used in CML. Bumetanide is a loop diuretic used to control edema of heart failure.

Question: 32

Which of the following drug classes are used to prevent and treat inflammatory

bowel disease (IBD)? I. Immunosuppressants II. Gamma amino butyric acid III. Corticosteroids IV. Macrolides

1. I and III only

2. II and III only

3. III and IV only

4. All of the above

Answer: A

Immunosuppressants and corticosteroids are commonly used to treat and prevent IBD.

Question: 33

A 56-year-old female patient has a diagnosis of GERD, mild hypertension, hyperthyroidism, hypercholesterolemia, and Type II diabetes of 5 years duration. Medications include metformin, glyburide, propylthiouracil, lansoprazole, atorvastatin, and hydrochlorothiazide. Recent labs report an A1c of 9.8%, TSH of 2.7, Hgb of 12.2 and total cholesterol of 130mg/dL. A physical exam reveals a blood pressure of 128/76 and a resting heart rate of 98. The patient is complaining

of muscle cramps, fatigue, and thirst. Which of the following medications may need adjustment?

1. Metformin and glyburide

2. Propylthiouracil

3. Atorvastatin

4. Metformin, glyburide, and atorvastatin

Answer: D

The patient is showing signs and symptoms of uncontrolled diabetes (A1c increased thirst) and an adverse effect of statin use (muscle cramps, fatigue). Thyroid tests are within normal limits. The hypoglycemics and statin dosages should be adjusted.

Question: 34

Which of the following brand names is not correctly matched with its generic

name?

1. Sonata-Zaleplon

2. Accolate-Zafirlukast

3. Sanctura-Trospium

4. Levitra-Venlafaxine

Answer: D

The brand name of venlafaxine is Effexor. Levitra is the brand name of vardenafil. The others are correctly matched.

Question: 35

Which of the following are possible adverse effects of ramipril (Altace)? I. Heart

failure and hyperkalemia II. Angioedema and bronchospasm III. Respiratory depression and coma IV. Paradoxical acid reflux and esophagitis

1. I and II only

2. II and III only

3. I and III only

4. All of the above are possible adverse effects.

Answer: A

Ramipril is an Angiotensin Converting Enzyme (ACE) Inhibitor. Adverse effects include heart failure, MI, hyperkalemia, angioedema, bronchospasm, anaphylaxis, and agranulocytosis.