ABAI Exam Information and Outline
American Board of Allergy and Immunology
Syllabus Update Checked on: November 9, 2026
ABAI Exam Syllabus & Study Guide
Before you start practicing with our exam simulator, it is essential to understand the
official ABAI exam objectives. This course outline serves as your roadmap.
The information below reflects the 2026 syllabus defined by
ABAI.
Below are complete topics detail with latest syllabus and course outline, that will help you good knowledge about exam objectives and topics that you have to prepare. These contents are covered in questions and answers pool of exam.
- Exam Format
- Single-day, computer-based, single-best-answer multiple-choice exam
- Approximately 75% clinical content and 25% basic science content
- Allergy / Hypersensitivity Disorders
- Asthma
- Pathophysiology, diagnosis, pulmonary function testing
- Pharmacotherapy and biologic therapies; exacerbation management
- Allergic and non-allergic rhinitis, sinusitis and nasal polyps
- Allergic conjunctivitis and ocular allergy
- Atopic dermatitis and contact dermatitis
- Urticaria and angioedema, including hereditary angioedema
- Anaphylaxis
- Triggers, diagnosis, epinephrine management, mast cell disorders
- Food allergy
- IgE-mediated food allergy, oral immunotherapy, FPIES
- Eosinophilic esophagitis and eosinophilic disorders
- Drug allergy
- Penicillin and beta-lactam allergy evaluation; drug challenges and desensitization
- Severe cutaneous adverse reactions (SJS/TEN, DRESS)
- Stinging insect hypersensitivity and venom immunotherapy
- Allergen immunotherapy
- Allergen extracts, dosing schedules, safety and adverse reactions
- Occupational and environmental allergic disease
- Hypersensitivity pneumonitis and allergic bronchopulmonary aspergillosis
- Asthma
- Immunological Disorders
- Primary immunodeficiencies (inborn errors of immunity)
- Antibody deficiencies, combined immunodeficiencies, phagocyte and complement disorders
- Immunoglobulin replacement therapy; hematopoietic stem cell transplantation
- Secondary immunodeficiency
- Autoimmune and autoinflammatory disorders
- Vasculitis and immune-mediated systemic disease
- Transplantation immunology
- Vaccines and immunization
- Primary immunodeficiencies (inborn errors of immunity)
- Basic Science (integrated, approx. 25%)
- Innate and adaptive immunity
- Immunoglobulins, cytokines, chemokines and receptors
- Mast cells, basophils and eosinophils
- Immunogenetics and HLA
- Diagnostic laboratory immunology: skin testing, specific IgE, flow cytometry
- Immunopharmacology and biologics
- Emerging National Health Priorities
- Opioid crisis, healthcare disparities, quality and patient safety
- Research methods, biostatistics and ethics