INCC-CRNI Exam Information and Outline
Certified Registered Nurse Infusion (CRNI)
INCC-CRNI Exam Syllabus & Study Guide
Before you start practicing with our exam simulator, it is essential to understand the
official INCC-CRNI exam objectives. This course outline serves as your roadmap.
The information below reflects the 2026 syllabus defined by
INCC.
Below are complete topics detail with latest syllabus and course outline, that will help you good knowledge about exam objectives and topics that you have to prepare. These contents are covered in questions and answers pool of exam.
Exam Code: CRNI
Exam Name: INCC CRNI Certified Registered Nurse Infusion (CRNI)
Total Questions: 140 multiple-choice questions.
Scored Questions: 120 questions.
Unscored Questions: 20 pretest questions (these are distributed randomly and do not affect your score).
Time Allotted: 2.5 hours (150 minutes).
Passing Mark: A scaled score of 70 is required to pass.
Format: Computer-based testing (CBT) at PSI/AMP testing centers.
1. Principals of Practice
- Anatomy and Physiology
- Infection Prevention and Control
- Epidemiology
- Chain of infection (e.g., standard precautions)
- Blood stream infections (e.g., CLABSI, CRBSI)
- Phlebotomy
- Blood sampling
- Therapeutic
2. Access Devices
- Technology and Clinical Applications
- Equipment
- Solution containers
- Administration sets
- Filters
- Add-on devices
- Administration devices (electronic, nonelectronic)
- Vein location devices (e.g., transillumination, ultrasound)
- Navigational tools (e.g., tip locating system)
- Infusion Access Devices
- Peripheral
- Short peripheral
- Midline
- Central
- Peripherally inserted central catheter (PICC)
- Tunneled
- Non-tunneled
- Implanted (i.e., ports)
- Subcutaneous
- Special Populations
- Older adults
- Pregnancy
- Chronic renal conditions
3. Infusion Therapies
- Pain Management
- Cardiovascular
- Antineoplastic
- Biologics/Immunologic
- Anti-infectives
- Blood Products
- Fluid and Electrolyte Balance
- Body composition
- Fluid volume excess and deficit
- Electrolyte disorders
- Maintenance and replacement
- Parenteral Nutrition
- General solution composition
- Formulas
- Additives
- Complications
- Infectious
- Metabolic
CRNI Tasks
- Assess the patient’s clinical condition and disease state
- Review patient’s medical history
- Review laboratory and other diagnostic data
- Apply anatomy and physiology principles to the therapy plan
- Verify patient identity
- Obtain or confirm informed consent
- Participate in patient care planning with the collaborative healthcare team
- Maintain established infection control practices
- Select devices and equipment based on therapy and characteristics of the patient
- Insert access device
- Monitor access device
- Educate patient and/or caregivers regarding therapy
- Verify appropriateness of therapy
- Verify matching of the product to the patient
- Administer therapy
- Evaluate patient’s response to therapy
- Perform care and maintenance based on access type
- Assess and troubleshoot access devices
- Identify and manage complications (local and systemic)
- Discontinue therapy
- Remove the access device
- Dispose of hazardous materials
- Document processes and procedures
- Participate in product evaluation
- Practice based on laws and regulatory agencies (e.g., OSHA, TJC)
- Incorporate and apply evidence-based practice (e.g., standards, guidelines, policies and procedures)
- Participate in performance improvement process