ENP-BC Exam Information and Outline
Emergency Nurse Practitioner (ENP)
Syllabus Update Checked on: November 11, 2026
ENP-BC Exam Syllabus & Study Guide
Before you start practicing with our exam simulator, it is essential to understand the
official ENP-BC exam objectives. This course outline serves as your roadmap.
The information below reflects the 2026 syllabus defined by
AANPCB.
Below are complete topics detail with latest syllabus and course outline, that will help you good knowledge about exam objectives and topics that you have to prepare. These contents are covered in questions and answers pool of exam.
- Exam Format
- 150 multiple-choice questions (135 scored, 15 unscored pretest)
- Duration: 3 hours
- Domain 01: Medical Screening (16%)
- Focused history and physical based on chief complaint
- Establish patient acuity and need for rapid intervention
- Domain 02: Medical Decision Making / Differential Diagnosis (24%)
- Identify differentials by likelihood of occurrence
- Prioritize by risk of morbidity or mortality
- Evaluate diagnostic studies against the differentials
- Domain 03: Patient Management (36%)
- Rapid resuscitation and stabilization
- Prescribe pharmacologic agents; initiate non-pharmacologic interventions
- Perform diagnostic and therapeutic procedures
- Consult other providers and re-evaluate changes in condition
- Manage multiple patients of varying acuity simultaneously
- Domain 04: Transitions of Care (16%)
- Timely disposition: admission, discharge, observation or transfer
- Disposition plans with appropriate resource use
- Engage patients and caregivers in transitions
- Domain 05: Professional Practices (8%)
- Diverse, equitable and inclusive practices; vulnerable populations
- EMTALA
- Professional, ethical, quality, safety and regulatory/legal standards
- Patient Conditions
- Abdominal and Gastrointestinal Disorders (13%)
- Cardiovascular Disorders (11%)
- Thoracic-Respiratory Disorders (10%)
- Ear, Eye, Nose, Oral/Dental and Throat Disorders (8%)
- Traumatic Disorders (8%)
- Musculoskeletal Disorders, non-traumatic (7%)
- Renal / Genitourinary Disorders (7%)
- Cutaneous Disorders (6%)
- Neurological Disorders (6%)
- Psychobehavioral Disorders (6%)
- Obstetrics and Gynecology (5%)
- Systemic Infections, Hematologic and Immune Disorders (5%)
- Endocrine, Metabolic and Nutritional Disorders (5%)
- Environmental and Toxicological Disorders (3%)
- Knowledge Areas
- Anatomy, physiology and pathophysiology
- Medical screening examination; focused history and physical
- Diagnostic studies (EKG, radiology, body fluid analysis)
- Pharmacological and integrative therapies
- Consultation, collaboration, patient and family education
- Documentation, coding and billing; resource utilization
- Pre-hospital and EMS; disaster and mass casualty management
- Health equity, epidemiology and social determinants of health
- Safety, harm reduction, prioritization, disposition and forensics
- Procedures
- Airway: intubation, mechanical and non-invasive ventilation, surgical airway
- Resuscitation: CPR, central venous and intraosseous access, defibrillation, neonatal/pediatric resuscitation
- Anesthesia and acute pain: local anesthesia, procedural sedation, regional nerve blocks
- Cardiovascular/thoracic: pacing, pericardiocentesis, cardioversion, thoracentesis, thoracostomy, ECG interpretation
- Cutaneous: incision and drainage, wound closure, escharotomy
- HEENT: epistaxis control, tonometry, slit lamp exam, lateral canthotomy, corneal foreign body removal
- Musculoskeletal: arthrocentesis, fracture/dislocation reduction, compartment pressure, fasciotomy
- Neurologic: lumbar puncture
- OB/GYN: pelvic and sexual assault exams, precipitous delivery, perimortem C-section
- Other: point-of-care ultrasound, foreign body removal, forensic evidence handling, imaging interpretation