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Exam Code: NNP-BC
Exam Name: NCC Neonatal Nurse Practitioner
Exam Type: Computer-based, multiple-choice questions.
Number of Questions: 175 questions (150 scored, 25 unscored pretest questions).
Time Allotted: 3 hours (180 minutes).
Passing Score: Scaled score of 700 (on a scale of 300–900).

- Maternal History affecting the Newborn Antepartum
- Neonatal complications: maternal risk factors & complications
- gestational hypertension
- cardiac/pulmonary disease
- diabetes
- common infectious diseases
- common hematologic diseases
- placental insufficiency
- substance abuse
- medication effects
- Fetal assessment
- fetal fibronectin
- nonstress test
- biophysical profile
- ultrasound/doppler flow
- amniocentesis
- antenatal screening/quad screen
- Fetal procedures
- Intrapartum
- Fetal Heart Rate (FHR) Patterns
- Effects on the Fetus/Neonate
- tocolysis/induction
- analgesia
- anesthesia
- neuroprotective agents
- Intrapartum Complications
- amniotic fluid volume
- oligohydramnios
- polyhydramnios
- Rupture of Membranes
- premature
- prolonged
- Intrauterine Drug Exposure
- Nicotine
- Alcohol
- Prescription/nonprescription
- Illicit Drug

- Neonatal
- General appearance
- Head, eyes, nose, ears and mouth
- Neck and throat
- Chest
- Abdomen
- Spine/back
- Extremities
- Genitalia
- Musculoskeletal
- Skin
- Vital signs
- Gestational age assessment physical Characteristics of
- preterm
- term
- post-term
- AGA
- SGA
- LGA

- Associated risks/Complications of variations in gestational age
- Abnormalities of intrauterine parameters
- Behavioral assessment
- state
- Muscle movement/tone/reflexes
- Autonomic control/responses
- Neurosensory capabilities
- Neurological assessment
- Clinical Laboratory Tests
- Microbiological
- Biochemical
- Hematological
- Endocrine
- Immunologic
- Genetic

- Diagnostic studies
- Ultrasound/Doppler
- CT scan
- MRI
- X-ray/fluoroscopy
- EKG
- EEG
- Echocardiogram
- Voiding Cystourethrogram

- Techniques & Equipment
- Procedures
- bag and mask ventilation and T-piece
- LMA’s
- endotracheal intubation
- umbilical vessel and peripheral catheterization
- chest tube insertion/removal
- needle aspiration
- spinal/lumbar tap
- intraosseous access
- intravenous line placement (central/peripheral)
- blood sampling
- circumcisions - complications/contraindications

- Equipment
- cardiopulmonary monitors
- oxygenation equipment/end tidal CO2 monitoring
- invasive/non-invasive blood gas monitoring
- indwelling catheters
- incubators/radiant warmers
- ventilators
- phototherapy
- NIRS

- Family Integration
- Communication
- Family centered care
- Barriers to parent/infant interaction
- Grieving Process
- Stages of grieving and common behaviors
- Factors influencing enhancement or impediment of grief process
- Palliative care/End of life
- Parental depression
- Periviability
- Diversity, Equity and Inclusion
• Culturally supportive care

- Discharge Planning and Follow Up
- Anticipatory guidance
- Follow up screening
- Hearing
- Vision - ROP
- Developmental
- Health risks
- Discharge preparation
- Follow-up care

- Thermoregulation
- Mechanisms and management of heat transfer
- evaporation
- conduction
- convection
- radiation
- Rewarming techniques
- Mechanisms of heat production
- Temperature assessment
- Neutral thermal environment

- Resuscitation and Stabilization
- Transition to extrauterine life
- Delivery room assessment
- Techniques of resuscitation
- Indications for interventions
- Cord blood gas interpretation
- Neonatal transport

- Growth and Nutrition
- Physiology of Digestion and Absorption
- Nutritional Requirements
- Enteral Feeding
- Parenteral Nutrition
- Composition of Breast Milk/Formulas/Donor milk
- Dietary Supplementation

- Fluids and Electrolytes
- Common problems and conditions
- Fluid & Electrolyte requirements
- Insensible water loss/gain
- Central & peripheral infusion
- Acid base balance
- Fish oil emulsion (Omegaven) SMOF

- Pharmacokinetics & Pharmacodynamics
- Pharmacokinetics
- distribution
- excretion
- absorption
- metabolism
- withdrawal
- Principles of administration
- dosage/interval
- route
- tolerance/weaning
- Common Drug Therapies
- Analgesia/narcotics
- Anticoagulants
- Anticonvulsants
- Antihypertensive drugs
- Antimicrobials
- biologics/immunities
- vaccinations
- Cardiovascular drugs
- vasodilators/vasopressors
- antidysrhythmia drugs
- Diuretics
- GI drugs
- antacids
- prokinetic
- proton pump inhibitors
- Inhalants
- iNO
- Neurologic agents
- anesthetics agents
- sedatives
- hypnotics
- Respiratory drugs
- bronchodilators
- respiratory stimulants
- surfactant therapy
- Steroids
- Drugs and breastfeeding
- Drug transfer
- Drug safety

- Cardiac
- Congenital Cardiac Defects
- cyanotic
- Ebstein’s Anomaly
- Tetralogy of Fallot
- truncus arteriosus
- transposition of great vessels
- total anomalous pulmonary venous return
- tricuspid atresia
- acyanotic
- ventricular septal defect
- coarctation of aorta (interrupted arch)
- atrial septal defect septal defect
- hypoplastic left heart syndrome
- endocardial cushion defect (AV canal)
- aortic stenosis
- Patent ductus arteriosus
- Congestive heart failure
- Hypertension/Hypotension
- Shock
- Dysrhythmias
- PGE’s

- Respiratory
- Respiratory distress syndrome
- Transient tachypnea
- Pneumothorax and air leaks/chylothorax
- Congenital pulmonary airway malformation (CPAM)
- Cystic pulmonary
- Apnea of prematurity
- Meconium aspiration
- Diaphragmatic eventrations
- Persistent pulmonary hypertension
- Pneumonia
- Pulmonary hemorrhage
- Pulmonary hypoplasia
- Diaphragmatic hernia
- Chronic lung disease
- Laryngeal, tracheomalacia/stenosis
- Respiratory support
- principles and methods of oxygen
- administration/ventilation
- risk factors affecting oxygenation/ventilation
- oxyhemoglobin dissociation curve
- high frequency ventilation (HFV)
- extracorporeal membrane oxygenation (ECMO)
- nitric oxide
- neurally adjusted ventilatory assist (NAVA)
- nasal intermittent positive pressure ventilation (NIPPV)
- noninvasive ventilation (NIV)

- Gastrointestinal
- Development of the GI tract
- Digestive and absorptive disorders
- diarrhea/short gut
- Disorders of suck/swallow/motility
- GERD
- cleft lip palate
- Duodenal atresia
- tracheoesophageal fistula -esophageal atresia
- small left colon syndrome
- Hirschsprung disease
- volvulus
- imperforate anus
- pyloric stenosis
- Malabsorption/maldigestion
- Diarrhea/short gut
- Anomalies/obstruction of upper and lower GI tract
- small left colon syndrome
- Hirschsprung’s disease
- Abdominal wall defects
- gastroschisis -omphalocele
- Obstructions
- Perforations
- Meconium ileus
- Tracheoesophageal fistula
- Necrotizing enterocolitis
- Inguinal hernia
- Malrotaton

- Renal/Genitourinary
- Renal vein/artery thrombosis
- Acute renal failure/insufficiency
- Polycystic/multicystic dysplastic kidneys
- Urinary outflow tract obstruction
- Testicular torsion
- Exstrophy of the bladder
- Hypospadias/epispadias
- Hydronephrosis grading system/hydroureter

- Endocrine/Metabolic
- Adrenal disorders
- Ambiguous genitalia
- Calcium disorders
- Glucose disorders
- Magnesium disorders
- Phosphorus disorders
- Pituitary disorders
- Thyroid disorders
- Infants of diabetic mothers
- Osteopenia of prematurity

- Hematopoietic
- Hematological disorders
- anemia
- polycythemia
- platelet disorders
- coagulopathies
- vitamin K deficiency
- disseminated intravascular coagulation
- factor deficiencies
- neutropenia/neutrophilia
- Rh disease and ABO incompatibility
- Blood component therapy
- Jaundice and liver disease
- Hyperbilirubinemia (direct and indirect)
- Breastmilk jaundice
- Kernicterus
- Phototherapy
- Exchange transfusion
- Biliary atresia

- Infectious Diseases
- Normal immunologic function
- Common neonatal infections
- group B streptococcal
- e-coli
- staphylococcal
- klebsiella
- enterococcus
- candidiasis
- pseudomonas
- enterovirus
- respiratory syncytial virus (RSV)
- CMV
- hepatitis B
- toxoplasmosis
- herpes
- HIV/AIDS
- chlamydia
- gonorrhea
- syphilis
- varicella
- Neonatal sepsis
- SIRS
- Meningitis
- Septic shock
- Infection control and universal precautions
- MRSA/VRSE
- Osteomyelitis

- Musculoskeletal
- Abnormalities of the skeleton
- metatarsus adductus
- achondroplasia
- Clubfoot
- Developmental dysplasia of the hip
- Spinal abnormalities
- Musculoskeletal birth injuries
- fractures
- nerve damage
- torticollis
- Aperts, crouzon, etc.

- Integumentary
- General skin development and care
- Disorders
- ecchymosis -epidermolysis bullosa
- hemangiomas
- ichthyosis
- subcutaneous fat necrosis
- Milia/miliara
- Hyperpigmented macule
- Erythema toxicum
- Neonatal pustular melanosis
- Auricular tags
- Petechiae
- Port wine stain
- Hyper/hypopigmentation

- Genetics
- Genetic processes
- multifactorial inheritance
- nondisjunction
- translocation
- deletion/duplication
- sex linked inheritance
- Inborn errors of metabolism
- Hyperammonemia
- Newborn Screening
- galactosemia
- cystic fibrosis
- Chromosomal abnormalities/syndromes
- Trisomy 21
- Trisomy 13
- Trisomy 18
- Turner syndrome
- Beckwith-Wiedemann syndrome
- DiGeorge syndrome
- Osteogenesis imperfecta
- Potter sequence
- VATER/VACTERL
- CHARGE

- Neurological
- Perinatal – depression/asphyxia
- Hypoxic ischemic encephalopathy
- therapeutic hypothermia
- Cranial hemorrhages
- Hydrocephalus
- Neural tube defects
- Seizures
- Jitteriness
- Periventricular leukomalacia
- Auto regulation
- Cerebral palsy
- aEEG
- Near-infrared spectroscopy (NIRS)
- Congenital neuromuscular disorders
- Craniosynostosis
- Neurodevelopmental care

- Ears, Eyes, Nose and Throat
- Eyes
- eye prophylaxis
- cataracts
- coloboma
- glaucoma
- retinopathy of prematurity
- strabismus
- conjunctivitis
- Nose
- nasolacrimal duct obstruction
- choanal atresia
- deviated septum
- Ears
- malformations
- Mouth/throat
- cleft lip and palate
- micrognathia/retrognathia
- macroglossia
- airway obstruction
- Ethical Principles
- Autonomy
- Beneficence
- Non-maleficence
- Justice
- Professional/Legal Issues
- Professional
- Regulation
- Practice
- HIPPA
- Staffing issues
- Legal liability
- Consent
- Documentation/medical records
- Negligence/malpractice
- Evidence-based practice
- Terminology
- Reliability
- Validity
- Significance
- Levels of Evidence
- Quality Improvement
- Research utilization
- Neonatal Safety
- Communication
- Interprofessional practice