TCTCN Exam Information and Outline
Transplantation and Cellular Therapy Certified Nurse
Syllabus Update Checked on: November 3, 2026
TCTCN Exam Syllabus & Study Guide
Before you start practicing with our exam simulator, it is essential to understand the
official TCTCN exam objectives. This course outline serves as your roadmap.
The information below reflects the 2026 syllabus defined by
ONCC.
Below are complete topics detail with latest syllabus and course outline, that will help you good knowledge about exam objectives and topics that you have to prepare. These contents are covered in questions and answers pool of exam.
- Exam Format
- Multiple-choice examination; 3 hours
- Foundations of HCT and Cellular Therapy
- Indications and transplant types
- Donor Selection, Mobilization and Collection
- HLA matching and apheresis
- Conditioning Regimens and Infusion
- Myeloablative vs. reduced intensity
- Engraftment and Early Complications
- Infections, VOD/SOS, mucositis
- GVHD Prevention and Management
- Acute and chronic GVHD
- CAR-T and Immune Effector Cell Therapy Toxicities
- CRS and ICANS grading
- Survivorship, Psychosocial Care and Professional Practice
- Late effects and support